Phases of Hyperconnectivity and Hypoconnectivity in the Default Mode and Salience Networks Track with Amyloid and Tau in Clinically Normal Individuals

Alzheimer's disease (AD) is characterized by two hallmark molecular pathologies: amyloid aβ(1–42) and Tau neurofibrillary tangles. To date, studies of functional connectivity MRI (fcMRI) in individuals with preclinical AD have relied on associations with in vivo measures of amyloid pathology. W...

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Pubblicato in:J Neurosci
Autori principali: Schultz, Aaron P., Chhatwal, Jasmeer P., Hedden, Trey, Mormino, Elizabeth C., Hanseeuw, Bernard J., Sepulcre, Jorge, Huijbers, Willem, LaPoint, Molly, Buckley, Rachel F., Johnson, Keith A., Sperling, Reisa A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2017
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413178/
https://ncbi.nlm.nih.gov/pubmed/28314821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3263-16.2017
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