The impact of Aβ and tau on prospective cognitive decline in older individuals

OBJECTIVES: Amyloid-beta (Aβ) and tau pathologies are commonly observed among clinically normal older individuals at post-mortem and can now be detected with in vivo neuroimaging. The association and interaction of these proteinopathies with prospective cognitive decline in normal aging and preclini...

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Udgivet i:Ann Neurol
Main Authors: Sperling, Reisa A., Mormino, Elizabeth C., Schultz, Aaron P., Betensky, Rebecca A., Papp, Kathryn V., Amariglio, Rebecca E., Hanseeuw, Bernard J., Buckley, Rachel, Chhatwal, Jasmeer, Hedden, Trey, Marshall, Gad A., Quiroz, Yakeel T., Donovan, Nancy J., Jackson, Jonathan, Gatchel, Jennifer R., Rabin, Jennifer S., Jacobs, Heidi, Yang, Hyun-Sik, Properzi, Michael, Kirn, Dylan R., Rentz, Dorene M., Johnson, Keith A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402593/
https://ncbi.nlm.nih.gov/pubmed/30549303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25395
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