Sex, Amyloid, and APOEε4 and risk of cognitive decline in preclinical Alzheimer’s disease: findings from three well-characterized cohorts

INTRODUCTION: Our objective was to investigate the effect of sex on cognitive decline within the context of β-amyloid (Aβ) burden and apolipoprotein (APOE) genotype. METHODS: We analyzed sex-specific effects on Aβ-PET, APOE and rates of change on the Preclinical Alzheimer Cognitive Composite-5 (PACC...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Buckley, Rachel F., Mormino, Elizabeth C., Amariglio, Rebecca E., Properzi, Michael J., Rabin, Jennifer S., Lim, Yen Ying, Papp, Kathryn V., Jacobs, Heidi I. L., Burnham, Samantha, Hanseeuw, Bernard J., Doré, Vincent, Dobson, Annette, Masters, Colin L., Waller, Michael, Rowe, Christopher C., Maruff, Paul, Donohue, Michael C., Rentz, Dorene M., Kirn, Dylan, Hedden, Trey, Chhatwal, Jasmeer, Schultz, Aaron P., Johnson, Keith A., Villemagne, Victor L., Sperling, Reisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131023/
https://ncbi.nlm.nih.gov/pubmed/29803541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.04.010
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