Sex, Amyloid, and APOEε4 and risk of cognitive decline in preclinical Alzheimer’s disease: findings from three well-characterized cohorts

INTRODUCTION: Our objective was to investigate the effect of sex on cognitive decline within the context of β-amyloid (Aβ) burden and apolipoprotein (APOE) genotype. METHODS: We analyzed sex-specific effects on Aβ-PET, APOE and rates of change on the Preclinical Alzheimer Cognitive Composite-5 (PACC...

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Pubblicato in:Alzheimers Dement
Autori principali: Buckley, Rachel F., Mormino, Elizabeth C., Amariglio, Rebecca E., Properzi, Michael J., Rabin, Jennifer S., Lim, Yen Ying, Papp, Kathryn V., Jacobs, Heidi I. L., Burnham, Samantha, Hanseeuw, Bernard J., Doré, Vincent, Dobson, Annette, Masters, Colin L., Waller, Michael, Rowe, Christopher C., Maruff, Paul, Donohue, Michael C., Rentz, Dorene M., Kirn, Dylan, Hedden, Trey, Chhatwal, Jasmeer, Schultz, Aaron P., Johnson, Keith A., Villemagne, Victor L., Sperling, Reisa A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131023/
https://ncbi.nlm.nih.gov/pubmed/29803541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.04.010
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