Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD

INTRODUCTION: Demonstrating the “clinical meaningfulness” of slowing early cognitive decline in clinically normal (CN) older adults with elevated amyloid-β (Aβ+) is critical for Alzheimer’s disease (AD) secondary prevention trials and for understanding early cognitive progression. METHODS: Cox regre...

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Vydáno v:Alzheimers Dement
Hlavní autoři: Papp, Kathryn V., Buckley, Rachel, Mormino, Elizabeth, Maruff, Paul, Villemagne, Victor L., Masters, Colin, Johnson, Keith A., Rentz, Dorene M., Sperling, Reisa A., Amariglio, Rebecca E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067681/
https://ncbi.nlm.nih.gov/pubmed/31759879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2019.09.074
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