A conceptualization of the utility of subjective cognitive decline in clinical trials of preclinical Alzheimer’s disease

INTRODUCTION: This commentary outlines a conceptual model for subjective cognitive decline (SCD) in relation to Alzheimer’s disease (AD) biomarkers in the preclinical stages of disease, and a framework for effectively utilizing SCD in secondary prevention clinical trials. OBJECTIVE: Mounting evidenc...

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Pubblicato in:J Mol Neurosci
Autori principali: Buckley, Rachel F., Villemagne, Victor L., Masters, Colin L., Ellis, Kathryn A., Rowe, Christopher C., Johnson, Keith, Sperling, Reisa, Amariglio, Rebecca
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241130/
https://ncbi.nlm.nih.gov/pubmed/27514526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-016-0810-z
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