Functional network integrity presages cognitive decline in preclinical Alzheimer disease

OBJECTIVE: To examine the utility of resting-state functional connectivity MRI (rs-fcMRI) measurements of network integrity as a predictor of future cognitive decline in preclinical Alzheimer disease (AD). METHODS: A total of 237 clinically normal older adults (aged 63–90 years, Clinical Dementia Ra...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Buckley, Rachel F., Schultz, Aaron P., Hedden, Trey, Papp, Kathryn V., Hanseeuw, Bernard J., Marshall, Gad, Sepulcre, Jorge, Smith, Emily E., Rentz, Dorene M., Johnson, Keith A., Sperling, Reisa A., Chhatwal, Jasmeer P.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496516/
https://ncbi.nlm.nih.gov/pubmed/28592457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004059
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