Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured by Positron Emission Tomography in Clinically Normal Older Adults

IMPORTANCE: Mounting evidence suggests that sex differences exist in the pathologic trajectory of Alzheimer disease. Previous literature shows elevated levels of cerebrospinal fluid tau in women compared with men as a function of apolipoprotein E (APOE) ε4 status and β-amyloid (Aβ). What remains unc...

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Detalles Bibliográficos
Publicado en:JAMA Neurol
Main Authors: Buckley, Rachel F., Mormino, Elizabeth C., Rabin, Jennifer S., Hohman, Timothy J., Landau, Susan, Hanseeuw, Bernard J., Jacobs, Heidi I. L., Papp, Kathryn V., Amariglio, Rebecca E., Properzi, Michael J., Schultz, Aaron P., Kirn, Dylan, Scott, Matthew R., Hedden, Trey, Farrell, Michelle, Price, Julie, Chhatwal, Jasmeer, Rentz, Dorene M., Villemagne, Victor L., Johnson, Keith A., Sperling, Reisa A.
Formato: Artigo
Idioma:Inglês
Publicado: American Medical Association 2019
Assuntos:
Original Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515599/
https://ncbi.nlm.nih.gov/pubmed/30715078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2018.4693
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