Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured by Positron Emission Tomography in Clinically Normal Older Adults

IMPORTANCE: Mounting evidence suggests that sex differences exist in the pathologic trajectory of Alzheimer disease. Previous literature shows elevated levels of cerebrospinal fluid tau in women compared with men as a function of apolipoprotein E (APOE) ε4 status and β-amyloid (Aβ). What remains unc...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Buckley, Rachel F., Mormino, Elizabeth C., Rabin, Jennifer S., Hohman, Timothy J., Landau, Susan, Hanseeuw, Bernard J., Jacobs, Heidi I. L., Papp, Kathryn V., Amariglio, Rebecca E., Properzi, Michael J., Schultz, Aaron P., Kirn, Dylan, Scott, Matthew R., Hedden, Trey, Farrell, Michelle, Price, Julie, Chhatwal, Jasmeer, Rentz, Dorene M., Villemagne, Victor L., Johnson, Keith A., Sperling, Reisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515599/
https://ncbi.nlm.nih.gov/pubmed/30715078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2018.4693
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