Sex, Amyloid, and APOEε4 and risk of cognitive decline in preclinical Alzheimer’s disease: findings from three well-characterized cohorts

INTRODUCTION: Our objective was to investigate the effect of sex on cognitive decline within the context of β-amyloid (Aβ) burden and apolipoprotein (APOE) genotype. METHODS: We analyzed sex-specific effects on Aβ-PET, APOE and rates of change on the Preclinical Alzheimer Cognitive Composite-5 (PACC...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Alzheimers Dement
المؤلفون الرئيسيون: Buckley, Rachel F., Mormino, Elizabeth C., Amariglio, Rebecca E., Properzi, Michael J., Rabin, Jennifer S., Lim, Yen Ying, Papp, Kathryn V., Jacobs, Heidi I. L., Burnham, Samantha, Hanseeuw, Bernard J., Doré, Vincent, Dobson, Annette, Masters, Colin L., Waller, Michael, Rowe, Christopher C., Maruff, Paul, Donohue, Michael C., Rentz, Dorene M., Kirn, Dylan, Hedden, Trey, Chhatwal, Jasmeer, Schultz, Aaron P., Johnson, Keith A., Villemagne, Victor L., Sperling, Reisa A.
التنسيق: Artigo
اللغة:Inglês
منشور في: 2018
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131023/
https://ncbi.nlm.nih.gov/pubmed/29803541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.04.010
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