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Protein Z-dependent protease inhibitor (ZPI) is a physiologically significant inhibitor of prothrombinase function

Current thought holds that factor Xa (FXa) bound in the prothrombinase complex is resistant to regulation by protein protease inhibitors during prothrombin activation. Here we provide evidence that, contrary to this view, the FXa-specific serpin inhibitor, protein Z-dependent protease inhibitor (ZPI...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Huang, Xin, Swanson, Richard, Kroh, Heather K., Bock, Paul E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514612/
https://ncbi.nlm.nih.gov/pubmed/30918026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006787
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