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Protein Z-dependent protease inhibitor (ZPI) is a physiologically significant inhibitor of prothrombinase function
Current thought holds that factor Xa (FXa) bound in the prothrombinase complex is resistant to regulation by protein protease inhibitors during prothrombin activation. Here we provide evidence that, contrary to this view, the FXa-specific serpin inhibitor, protein Z-dependent protease inhibitor (ZPI...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6514612/ https://ncbi.nlm.nih.gov/pubmed/30918026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006787 |
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