Загрузка...
Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington’s disease treatment
DREAM, a neuronal calcium sensor protein, has multiple cellular roles including the regulation of Ca(2+) and protein homeostasis. We recently showed that reduced DREAM expression or blockade of DREAM activity by repaglinide is neuroprotective in Huntington’s disease (HD). Here we used structure-base...
Сохранить в:
| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6514012/ https://ncbi.nlm.nih.gov/pubmed/31086218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43677-7 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|