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Inhibition of the Neuronal Calcium Sensor DREAM Modulates Presenilin-2 Endoproteolysis
Deregulated intracellular Ca(2+) and protein homeostasis underlie synaptic dysfunction and are common features in neurodegenerative diseases. DREAM, also known as calsenilin or KChIP-3, is a multifunctional Ca(2+) binding protein of the neuronal calcium sensor superfamily with specific functions thr...
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| Veröffentlicht in: | Front Mol Neurosci |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6287014/ https://ncbi.nlm.nih.gov/pubmed/30559648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00449 |
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