The structural basis of translational control by eIF2 phosphorylation

Protein synthesis in eukaryotes is controlled by signals and stresses via a common pathway, called the integrated stress response (ISR). Phosphorylation of the translation initiation factor eIF2 alpha at a conserved serine residue mediates translational control at the ISR core. To provide insight in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Adomavicius, Tomas, Guaita, Margherita, Zhou, Yu, Jennings, Martin D., Latif, Zakia, Roseman, Alan M., Pavitt, Graham D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513899/
https://ncbi.nlm.nih.gov/pubmed/31086188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10167-3
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