A16 SENSING OF A MICROBIAL METABOLITE BY FIBROBLASTS THROUGH THE PREGNANE X RECEPTOR RESTRAINS INFLAMMATION AND FIBROSIS IN MICE

BACKGROUND: Fibrosis is a serious and irreversible complication of Crohn’s disease (CD) that can lead to intestinal obstruction and has no effective treatment beyond surgical resection. The pathogenesis of fibrosis is incompletely understood however, it is thought to involve an aberrant repair respo...

詳細記述

保存先:
書誌詳細
出版年:J Can Assoc Gastroenterol
主要な著者: Flannigan, K L, Nieves, K, Alston, L, Mani, S, Hirota, S A
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
Oral Presentations
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512679/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz006.015
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