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Development of EHop-016:A Small Molecule Inhibitor of Rac

The Rac inhibitor EHop-016 was developed as a compound with the potential to inhibit cancer metastasis. Inhibition of the first step of metastasis, migration, is an important strategy for metastasis prevention. The small GTPase Rac acts as a pivotal binary switch that is turned “on” by guanine nucle...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Enzymes
Egile Nagusiak: Dharmawardhane, Suranganie, Hernandez, Eliud, Vlaar, Cornelis
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512336/
https://ncbi.nlm.nih.gov/pubmed/25033803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-416749-0.00006-3
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