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Development of EHop-016:A Small Molecule Inhibitor of Rac
The Rac inhibitor EHop-016 was developed as a compound with the potential to inhibit cancer metastasis. Inhibition of the first step of metastasis, migration, is an important strategy for metastasis prevention. The small GTPase Rac acts as a pivotal binary switch that is turned “on” by guanine nucle...
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| Publicado no: | Enzymes |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6512336/ https://ncbi.nlm.nih.gov/pubmed/25033803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-416749-0.00006-3 |
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