Transcription factors IRF8 and PU.1 are required for follicular B cell development and BCL6-driven germinal center responses

The IRF and Ets families of transcription factors regulate the expression of a range of genes involved in immune cell development and function. However, the understanding of the molecular mechanisms of each family member has been limited due to their redundancy and broad effects on multiple lineages...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Hongsheng, Jain, Shweta, Li, Peng, Lin, Jian-Xin, Oh, Jangsuk, Qi, Chenfeng, Gao, Yuanyuan, Sun, Jiafang, Sakai, Tomomi, Naghashfar, Zohreh, Abbasi, Sadia, Kovalchuk, Alexander L., Bolland, Silvia, Nutt, Stephen L., Leonard, Warren J., Morse, Herbert C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511064/
https://ncbi.nlm.nih.gov/pubmed/31000603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901258116
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