Transcription factors IRF8 and PU.1 are required for follicular B cell development and BCL6-driven germinal center responses

The IRF and Ets families of transcription factors regulate the expression of a range of genes involved in immune cell development and function. However, the understanding of the molecular mechanisms of each family member has been limited due to their redundancy and broad effects on multiple lineages...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Wang, Hongsheng, Jain, Shweta, Li, Peng, Lin, Jian-Xin, Oh, Jangsuk, Qi, Chenfeng, Gao, Yuanyuan, Sun, Jiafang, Sakai, Tomomi, Naghashfar, Zohreh, Abbasi, Sadia, Kovalchuk, Alexander L., Bolland, Silvia, Nutt, Stephen L., Leonard, Warren J., Morse, Herbert C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2019
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511064/
https://ncbi.nlm.nih.gov/pubmed/31000603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901258116
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