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Expression of IRF8 in gastric epithelial cells confers protective innate immunity against Helicobacter pylori infection

Interferon regulatory factor 8 (IRF8) is expressed in many types of blood cells and plays critical roles in cellular differentiation and function. However, the role of IRF8 in nonhematopoietic systems remains poorly understood. In this study, we provide evidence that IRF8 is a transcriptional modula...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Yan, Ming, Wang, Hongsheng, Sun, Jiafang, Liao, Wei, Li, Peng, Zhu, Yin, Xu, Chengfu, Joo, Jungsoo, Sun, Yan, Abbasi, Sadia, Kovalchuk, Alexander, Lv, Nonghua, Leonard, Warren J., Morse, Herbert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761481/
https://ncbi.nlm.nih.gov/pubmed/26843324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500766
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