IFN Regulatory Factor 8 Regulates MDM2 in Germinal Center B Cells

IFN regulatory factor 8 (IRF8) is a transcription factor that affects the differentiation and function of myeloid, dendritic, and B cells. Herein we report that IRF8 regulates the expression of Mdm2, a suppressor of p53-dependent and -independent apoptosis pathways, in germinal center (GC) B cells....

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Zhou, Jeff X., Lee, Chang Hoon, Qi, Chen Feng, Wang, Hongsheng, Naghashfar, Zohreh, Abbasi, Sadia, Morse, Herbert C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759298/
https://ncbi.nlm.nih.gov/pubmed/19648273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803693
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky