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IFN Regulatory Factor 8 Regulates MDM2 in Germinal Center B Cells
IFN regulatory factor 8 (IRF8) is a transcription factor that affects the differentiation and function of myeloid, dendritic, and B cells. Herein we report that IRF8 regulates the expression of Mdm2, a suppressor of p53-dependent and -independent apoptosis pathways, in germinal center (GC) B cells....
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759298/ https://ncbi.nlm.nih.gov/pubmed/19648273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803693 |
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