Exploratory trial of a biepitopic CAR T-targeting B cell maturation antigen in relapsed/refractory multiple myeloma

Relapsed and refractory (R/R) multiple myeloma (MM) patients have very poor prognosis. Chimeric antigen receptor modified T (CAR T) cells is an emerging approach in treating hematopoietic malignancies. Here we conducted the clinical trial of a biepitope-targeting CAR T against B cell maturation anti...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Xu, Jie, Chen, Li-Juan, Yang, Shuang-Shuang, Sun, Yan, Wu, Wen, Liu, Yuan-Fang, Xu, Ji, Zhuang, Yan, Zhang, Wu, Weng, Xiang-Qin, Wu, Jing, Wang, Yan, Wang, Jin, Yan, Hua, Xu, Wen-Bin, Jiang, Hua, Du, Juan, Ding, Xiao-Yi, Li, Biao, Li, Jun-Min, Fu, Wei-Jun, Zhu, Jiang, Zhu, Li, Chen, Zhu, Fan, Xiao-Hu (Frank), Hou, Jian, Li, Jian-Yong, Mi, Jian-Qing, Chen, Sai-Juan
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510991/
https://ncbi.nlm.nih.gov/pubmed/30988175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1819745116
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