DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1

BACKGROUND: DNMT3A mutations are frequently discovered in acute myeloid leukemia (AML), associated with poor outcome. Recently, a relapse case report of AML extramedullary disease has showed that AML cells harboring DNMT3A variation were detected in the cerebral spinal fluid. However, whether a caus...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Xu, Jie, Zhang, Wu, Yan, Xiao-Jing, Lin, Xue-Qiu, Li, Wei, Mi, Jian-Qing, Li, Jun-Min, Zhu, Jiang, Chen, Zhu, Chen, Sai-Juan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057205/
https://ncbi.nlm.nih.gov/pubmed/27724883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0337-3
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