GluA1 signal peptide determines the spatial assembly of heteromeric AMPA receptors

AMPA-type glutamate receptors (AMPARs) mediate fast excitatory neurotransmission and predominantly assemble as heterotetramers in the brain. Recently, the crystal structures of homotetrameric GluA2 demonstrated that AMPARs are assembled with two pairs of conformationally distinct subunits, in a dime...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: He, Xue-Yan, Li, Yan-Jun, Kalyanaraman, Chakrapani, Qiu, Li-Li, Chen, Chen, Xiao, Qi, Liu, Wen-Xue, Zhang, Wei, Yang, Jian-Jun, Chen, Guiquan, Jacobson, Matthew P., Shi, Yun Stone
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2016
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PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035880/
https://ncbi.nlm.nih.gov/pubmed/27601647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524358113
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