GluA1 signal peptide determines the spatial assembly of heteromeric AMPA receptors

AMPA-type glutamate receptors (AMPARs) mediate fast excitatory neurotransmission and predominantly assemble as heterotetramers in the brain. Recently, the crystal structures of homotetrameric GluA2 demonstrated that AMPARs are assembled with two pairs of conformationally distinct subunits, in a dime...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: He, Xue-Yan, Li, Yan-Jun, Kalyanaraman, Chakrapani, Qiu, Li-Li, Chen, Chen, Xiao, Qi, Liu, Wen-Xue, Zhang, Wei, Yang, Jian-Jun, Chen, Guiquan, Jacobson, Matthew P., Shi, Yun Stone
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035880/
https://ncbi.nlm.nih.gov/pubmed/27601647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524358113
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