GluA1 signal peptide determines the spatial assembly of heteromeric AMPA receptors

AMPA-type glutamate receptors (AMPARs) mediate fast excitatory neurotransmission and predominantly assemble as heterotetramers in the brain. Recently, the crystal structures of homotetrameric GluA2 demonstrated that AMPARs are assembled with two pairs of conformationally distinct subunits, in a dime...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: He, Xue-Yan, Li, Yan-Jun, Kalyanaraman, Chakrapani, Qiu, Li-Li, Chen, Chen, Xiao, Qi, Liu, Wen-Xue, Zhang, Wei, Yang, Jian-Jun, Chen, Guiquan, Jacobson, Matthew P., Shi, Yun Stone
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2016
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035880/
https://ncbi.nlm.nih.gov/pubmed/27601647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524358113
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