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Lysosomal targeting of the ABC transporter TAPL is determined by membrane-localized charged residues
The human lysosomal polypeptide ABC transporter TAPL (ABC subfamily B member 9, ABCB9) transports 6–59-amino-acid-long polypeptides from the cytosol into lysosomes. The subcellular localization of TAPL depends solely on its N-terminal transmembrane domain, TMD0, which lacks conventional targeting se...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509505/ https://ncbi.nlm.nih.gov/pubmed/30877195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007071 |
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