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Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL
The ATP-binding cassette transporter TAPL translocates polypeptides from the cytosol into the lysosomal lumen. TAPL can be divided into two functional units: coreTAPL, active in ATP-dependent peptide translocation, and the N-terminal membrane spanning domain, TMD0, responsible for cellular localizat...
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| Yayımlandı: | Sci Rep |
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| Asıl Yazarlar: | , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6199259/ https://ncbi.nlm.nih.gov/pubmed/30353140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33841-w |
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