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Peptide translocation by the lysosomal ABC transporter TAPL is regulated by coupling efficiency and activation energy
The lysosomal polypeptide transporter TAPL belongs to the superfamily of ATP-binding cassette transporters. TAPL forms a homodimeric transport complex, which translocates oligo- and polypeptides into the lumen of lysosomes driven by ATP hydrolysis. Although the structure and the function of ABC tran...
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| Yayımlandı: | Sci Rep |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6695453/ https://ncbi.nlm.nih.gov/pubmed/31417173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48343-6 |
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