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Evidence That Ternary Complex (eIF2-GTP-tRNA(i)(Met))–Deficient Preinitiation Complexes Are Core Constituents of Mammalian Stress Granules
Environmental stress-induced phosphorylation of eIF2α inhibits protein translation by reducing the availability of eIF2-GTP-tRNA(i)Met, the ternary complex that joins initiator tRNA(Met) to the 43S preinitiation complex. The resulting untranslated mRNA is dynamically routed to discrete cytoplasmic f...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Cell Biology
2002
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC65082/ https://ncbi.nlm.nih.gov/pubmed/11809833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-05-0221 |
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