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Initiation Factor eIF2γ Promotes eIF2–GTP–Met-tRNA(i)(Met) Ternary Complex Binding to the 40S Ribosome
In contrast to elongation factor EF-Tu, which delivers aminoacyl-tRNAs to the ribosomal A-site, eukaryotic initiation factor eIF2 binds initiator Met-tRNA(i)(Met) to the P-site of the 40S ribosomal subunit. We used directed hydroxyl radical probing experiments to map the binding of Saccharomyces cer...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210414/ https://ncbi.nlm.nih.gov/pubmed/22002225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2133 |
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