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MEHMO syndrome mutation EIF2S3-I259M impairs initiator Met-tRNA(i)(Met) binding to eukaryotic translation initiation factor eIF2
The heterotrimeric eukaryotic translation initiation factor (eIF) 2 plays critical roles in delivering initiator Met-tRNA(i)(Met) to the 40S ribosomal subunit and in selecting the translation initiation site. Genetic analyses of patients with MEHMO syndrome, an X-linked intellectual disability syndr...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344876/ https://ncbi.nlm.nih.gov/pubmed/30517694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1213 |
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