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Developmental features of DNA methylation in CpG islands of human gametes and preimplantation embryos

The aim of current study was to apply the methylated DNA immunoprecipitation (MeDIP)-Chip method to investigate dynamic changes in CpG island methylation in human sperm, oocytes and various developmental stages of preimplantation embryos. Samples were divided into eight groups: 1, sperm (n=30); 2, M...

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Detalles Bibliográficos
Publicado en:Exp Ther Med
Main Authors: Huang, Yuling, Liu, Haiying, Du, Hongzhi, Zhang, Wenhong, Kang, Xianjing, Luo, Yang, Zhou, Xueliang, Li, Lei
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507515/
https://ncbi.nlm.nih.gov/pubmed/31105782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7523
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