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Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism
Fidgetin is a microtubule-severing protein that pares back the labile domains of microtubules in the axon. Experimental depletion of fidgetin results in elongation of the labile domains of microtubules and faster axonal growth. To test whether fidgetin knockdown assists axonal regeneration, we plate...
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| Publié dans: | J Neurosci |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6507085/ https://ncbi.nlm.nih.gov/pubmed/30647150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1888-18.2018 |
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