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Vertebrate Fidgetin Restrains Axonal Growth by Severing Labile Domains of Microtubules
Individual microtubules (MTs) in the axon consist of a stable domain that is highly acetylated and a labile domain that is not. Traditional MT-severing proteins preferentially cut the MT in the stable domain. In Drosophila, fidgetin behaves in this fashion, with targeted knockdown resulting in neuro...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Rep |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837332/ https://ncbi.nlm.nih.gov/pubmed/26344772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.017 |
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