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Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism

Fidgetin is a microtubule-severing protein that pares back the labile domains of microtubules in the axon. Experimental depletion of fidgetin results in elongation of the labile domains of microtubules and faster axonal growth. To test whether fidgetin knockdown assists axonal regeneration, we plate...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Matamoros, Andrew J., Tom, Veronica J., Wu, Di, Rao, Yash, Sharp, David J., Baas, Peter W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507085/
https://ncbi.nlm.nih.gov/pubmed/30647150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1888-18.2018
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