Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism

Fidgetin is a microtubule-severing protein that pares back the labile domains of microtubules in the axon. Experimental depletion of fidgetin results in elongation of the labile domains of microtubules and faster axonal growth. To test whether fidgetin knockdown assists axonal regeneration, we plate...

Full description

Saved in:
Bibliographic Details
Published in:J Neurosci
Main Authors: Matamoros, Andrew J., Tom, Veronica J., Wu, Di, Rao, Yash, Sharp, David J., Baas, Peter W.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2019
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507085/
https://ncbi.nlm.nih.gov/pubmed/30647150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1888-18.2018
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items