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Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism

Fidgetin is a microtubule-severing protein that pares back the labile domains of microtubules in the axon. Experimental depletion of fidgetin results in elongation of the labile domains of microtubules and faster axonal growth. To test whether fidgetin knockdown assists axonal regeneration, we plate...

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Foilsithe in:J Neurosci
Main Authors: Matamoros, Andrew J., Tom, Veronica J., Wu, Di, Rao, Yash, Sharp, David J., Baas, Peter W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507085/
https://ncbi.nlm.nih.gov/pubmed/30647150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1888-18.2018
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