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Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury
After a dorsal root crush injury, centrally-projecting sensory axons fail to regenerate across the dorsal root entry zone (DREZ) to extend into the spinal cord. We find that chemogenetic activation of adult dorsal root ganglion (DRG) neurons improves axon growth on an in vitro model of the inhibitor...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7705672/ https://ncbi.nlm.nih.gov/pubmed/33257677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19914-3 |
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