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Blockade of Nogo Receptor Ligands Promotes Functional Regeneration of Sensory Axons after Dorsal Root Crush

A major impediment for regeneration of axons within the CNS is the presence of multiple inhibitory factors associated with myelin. Three of these factors bind to the Nogo receptor, NgR, which is expressed on axons. Administration of exogenous blockers of NgR or NgR ligands promotes the regeneration...

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Détails bibliographiques
Auteurs principaux: Harvey, Pamela A., Lee, Daniel H. S., Qian, Fang, Weinreb, Paul H., Frank, Eric
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883456/
https://ncbi.nlm.nih.gov/pubmed/19439606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5885-08.2009
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