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Blockade of Nogo Receptor Ligands Promotes Functional Regeneration of Sensory Axons after Dorsal Root Crush

A major impediment for regeneration of axons within the CNS is the presence of multiple inhibitory factors associated with myelin. Three of these factors bind to the Nogo receptor, NgR, which is expressed on axons. Administration of exogenous blockers of NgR or NgR ligands promotes the regeneration...

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Detalhes bibliográficos
Main Authors: Harvey, Pamela A., Lee, Daniel H. S., Qian, Fang, Weinreb, Paul H., Frank, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883456/
https://ncbi.nlm.nih.gov/pubmed/19439606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5885-08.2009
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