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Blockade of Nogo Receptor Ligands Promotes Functional Regeneration of Sensory Axons after Dorsal Root Crush

A major impediment for regeneration of axons within the CNS is the presence of multiple inhibitory factors associated with myelin. Three of these factors bind to the Nogo receptor, NgR, which is expressed on axons. Administration of exogenous blockers of NgR or NgR ligands promotes the regeneration...

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Autores principales: Harvey, Pamela A., Lee, Daniel H. S., Qian, Fang, Weinreb, Paul H., Frank, Eric
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883456/
https://ncbi.nlm.nih.gov/pubmed/19439606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5885-08.2009
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