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Knockdown of Fidgetin Improves Regeneration of Injured Axons by a Microtubule-Based Mechanism
Fidgetin is a microtubule-severing protein that pares back the labile domains of microtubules in the axon. Experimental depletion of fidgetin results in elongation of the labile domains of microtubules and faster axonal growth. To test whether fidgetin knockdown assists axonal regeneration, we plate...
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| Pubblicato in: | J Neurosci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6507085/ https://ncbi.nlm.nih.gov/pubmed/30647150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1888-18.2018 |
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