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Mitochondrial dysfunction in C. elegans activates mitochondrial relocalization and nuclear hormone receptor-dependent detoxification genes

In Caenorhabditis elegans, mitochondrial dysfunction caused by mutation or toxins activates programs of detoxification and immune response. A genetic screen for mutations that constitutively induce C. elegans mitochondrial defense revealed reduction of function mutations in the mitochondrial chapero...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Mao, Kai, Ji, Fei, Breen, Peter, Sewell, Aileen, Han, Min, Sadreyev, Ruslan, Ruvkun, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506380/
https://ncbi.nlm.nih.gov/pubmed/30799287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.01.022
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