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Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response

RNA interference (RNAi) is an antiviral pathway common to many eukaryotes that detects and cleaves foreign nucleic acids. In mammals, mitochondrially localized proteins such as mitochondrial antiviral signaling (MAVS), retinoic acid-inducible gene I (RIG-I), and melanoma differentiation-associated p...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Mao, Kai, Breen, Peter, Ruvkun, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735679/
https://ncbi.nlm.nih.gov/pubmed/33264285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000996
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