Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs

Dicer enzymes process virus-specific double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) to initiate specific antiviral defense by related RNA interference (RNAi) pathways in plants, insects, nematodes, and mammals. Antiviral RNAi in Caenorhabditis elegans requires Dicer-related helicas...

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Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Coffman, Stephanie R., Lu, Jinfeng, Guo, Xunyang, Zhong, Jing, Jiang, Hongshan, Broitman-Maduro, Gina, Li, Wan-Xiang, Lu, Rui, Maduro, Morris, Ding, Shou-wei
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362034/
https://ncbi.nlm.nih.gov/pubmed/28325765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00264-17
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