Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs

Dicer enzymes process virus-specific double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) to initiate specific antiviral defense by related RNA interference (RNAi) pathways in plants, insects, nematodes, and mammals. Antiviral RNAi in Caenorhabditis elegans requires Dicer-related helicas...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Coffman, Stephanie R., Lu, Jinfeng, Guo, Xunyang, Zhong, Jing, Jiang, Hongshan, Broitman-Maduro, Gina, Li, Wan-Xiang, Lu, Rui, Maduro, Morris, Ding, Shou-wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362034/
https://ncbi.nlm.nih.gov/pubmed/28325765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00264-17
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