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Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in C. elegans by distinct mechanisms

RNAi-mediated antiviral immunity in Caenorhabditis elegans requires Dicer-related helicase 1 (DRH-1), which encodes the helicase and C-terminal domains homologous to the mammalian retinoic acid inducible gene I (RIG-I)-like helicase (RLH) family of cytosolic immune receptors. Here we show that the a...

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Hlavní autoři: Guo, Xunyang, Zhang, Rui, Wang, Jeffrey, Ding, Shou-Wei, Lu, Rui
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791698/
https://ncbi.nlm.nih.gov/pubmed/24043766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307453110
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