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RNA Interference Functions as an Antiviral Immunity Mechanism in Mammals

Diverse eukaryotic hosts produce virus-derived small interfering RNAs (siRNAs) to direct antiviral immunity by RNA interference (RNAi). However, it remains unknown whether the mammalian RNAi pathway has a natural antiviral function. Here, we show that infection of hamster cells and suckling mice by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Yang, Lu, Jinfeng, Han, Yanhong, Fan, Xiaoxu, Ding, Shou-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875315/
https://ncbi.nlm.nih.gov/pubmed/24115437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1241911
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