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The surveillance of pre-mRNA splicing is an early step in C. elegans RNAi of endogenous genes

RNAi pathways detect and silence foreign nucleic acids such as viruses as well as endogenous genes in many species. The phylogenetic profile across eukaryotes of proteins that mediate key steps in RNAi is correlated with the profiles of multiple mRNA splicing proteins and with intron number, suggest...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Newman, Martin A., Ji, Fei, Fischer, Sylvia E.J., Anselmo, Anthony, Sadreyev, Ruslan I., Ruvkun, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004069/
https://ncbi.nlm.nih.gov/pubmed/29739806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.311514.118
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