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Inactivation of conserved genes induces microbial aversion, drug detoxification, and innate immunity in C.elegans

The nematode C. elegans consumes benign bacteria such as E. coli and is repelled by pathogens and toxins. Here we show that RNAi and toxin-mediated disruption of core cellular activities, including translation, respiration, and protein turnover, stimulates behavioral avoidance of attractive E. coli....

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Detalhes bibliográficos
Main Authors: Melo, Justine A., Ruvkun, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613046/
https://ncbi.nlm.nih.gov/pubmed/22500807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.02.050
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