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Inactivation of conserved genes induces microbial aversion, drug detoxification, and innate immunity in C.elegans

The nematode C. elegans consumes benign bacteria such as E. coli and is repelled by pathogens and toxins. Here we show that RNAi and toxin-mediated disruption of core cellular activities, including translation, respiration, and protein turnover, stimulates behavioral avoidance of attractive E. coli....

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Détails bibliographiques
Auteurs principaux: Melo, Justine A., Ruvkun, Gary
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613046/
https://ncbi.nlm.nih.gov/pubmed/22500807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.02.050
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