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Next-generation sequencing for identification of EMS-induced mutations in Caenorhabditis elegans

Forward genetic analysis using chemical mutagenesis in model organisms is a powerful tool for investigation of molecular mechanisms in biological systems. In the nematode Caenorhabditis elegans mutagenesis screens using ethyl methanesulfonate (EMS) have led to important insights into genetic control...

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Bibliografische gegevens
Gepubliceerd in:Curr Protoc Mol Biol
Hoofdauteurs: Lehrbach, Nicolas J., Ji, Fei, Sadreyev, Ruslan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303615/
https://ncbi.nlm.nih.gov/pubmed/28060408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpmb.27
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