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HIF-1α regulates IL-1β and IL-17 in sarcoidosis

Sarcoidosis is a complex systemic granulomatous disease of unknown etiology characterized by the presence of activated macrophages and Th1/Th17 effector cells. Data mining of our RNA-Seq analysis of CD14(+)monocytes showed enrichment for metabolic and hypoxia inducible factor (HIF) pathways in sarco...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Talreja, Jaya, Talwar, Harvinder, Bauerfeld, Christian, Grossman, Lawrence I, Zhang, Kezhong, Tranchida, Paul, Samavati, Lobelia
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506207/
https://ncbi.nlm.nih.gov/pubmed/30946009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44519
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