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Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1β and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells

Sarcoidosis is a multisystem granulomatous disease of unknown etiology that primarily affects the lungs. Our previous work indicates that activation of p38 plays a pivotal role in sarcoidosis inflammatory response. Therefore, we investigated the upstream kinase responsible for activation of p38 in s...

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Pubblicato in:J Immunol
Autori principali: Talreja, Jaya, Talwar, Harvinder, Ahmad, Nisar, Rastogi, Ruchi, Samavati, Lobelia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975961/
https://ncbi.nlm.nih.gov/pubmed/27402699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600258
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