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MEK1 Dependent and Independent ERK Activation Regulates IL-10 and IL-12 Production in Bone Marrow Derived Macrophages
The mitogen activated protein kinases ERK1/2 play an important role in response to toll like receptor (TLR) activation and cytokine production, including IL-10 and IL-12. Here, we examined the role of MEK1 in ERK1/2 activation in response to TLR4 agonist by using bone marrow-derived macrophages (BMD...
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| Publicado no: | Cell Signal |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540637/ https://ncbi.nlm.nih.gov/pubmed/26208884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.07.015 |
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